The Andes Biotechnologies team are regular contributors to global scientific
Down regulation of the Antisense Mitochondrial ncRNAs is a Unique Vulnerability of Cancer Cells and a Potential Target for Cancer Therapy
J. Biol. Chem. 2014, Vol.289, No. 39, pp. 27182–27198, Aug 6 2014
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Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer
BMC Urology 2012, 12:37, Dec 18 2012
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Expression of Mitochondrial Non-coding RNAs (ncRNAs) Is Modulated by High Risk Human Papillomavirus (HPV) Oncogenes
J. Biol. Chem. 2012, Vol.287, No. 25, pp. 21303–21315, Jun 15 2012
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Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells
J. Cell. Oncol. 2011, Vol. 34, No.4, pp. 297–305, Feb 24 2011
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Expression of a family of noncoding mitochondrial RNAs distinguishes normal from cancer cells
Proc. Natl. Acad. Sci. 2009, USA,Vol.106, No.23, pp. 9430-9434, May 26 2009
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Expression of a novel non-coding mitochondrial RNA in human proliferating cells
Nucleic Acids Research 2007, Vol.35, No.21, pp. 7336-7347, Oct 25 2007
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Localization of the 16S mitochondrial rRNA in the nucleus of mammalian spermatogenic cells
Molecular Human Reproduction 2002, Vol.8, No.11, pp. 977-983, Nov 01 2002
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A putative RNA editing from U to C in a mouse mitochondrial transcript
Nucleic Acids Research 2002, Vol.30, No.9, pp. 1895-1901, May 01 2002
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Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model
Oncotarget, 2017, Vol. 8, No. 27, pp. 43692-43708, Jun 13 2017
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Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors
Oncotarget, 2017, Vol. 7, No. 36, pp. 58331-58350 , Aug 06 2016
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The Mitochondrial Antisense ncRNAs are Down-Regulated in Early Cervical Carcinoma
J. Cancer Sci. Ther. 2013, S7: 004, May 30 2013
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Non-Coding Mitochondrial RNAs (ncmtRNAs) in Gynecological and Urinary Malignancies: Universal Targets for Development of an Efficient Therapy?
Horizons in Cancer Research 2017, Vol. 65, Ch. 6, pp. 91-118, 2017
Human Papilloma Virus and Non-coding RNAs: From Basic to Diagnostic
Handbook on Human Papillomavirus 2013, Ch. 2, pp. 139-180, 2013
HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes.
Aging 2019, Vol. 11, No. 1. pp. 33 – 47
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Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors.
Cell Death and Disease, 2019, 10:423
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Targeting antisense mitochondrial noncoding RNAs induces bladder cancer cell death and inhibition of tumor growth through reduction of survival and invasion factors.
Journal of Cancer, 2020, Vol. 11.
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Exosomes released upon mitochondrial ASncmtRNA knockdown reduce tumorigenic properties of malignant breast cancer cells.
Scientific Reports Nature, 2020, 10:343
